徐美琦 博士
讲师
药学系教师
电话:15652934033 邮箱:xumq@zucc.edu.cn 办公地址:新葡萄8883官网AMG北校区理1-319
研究方向:药剂
个人简介
徐美琦,讲师,博士毕业于北京大学医学部,从事纳米靶向给药系统的研究开发,主要研究方向为以脂肪酸等小分子作为功能材料构建肿瘤微环境响应性化疗药物前药自组装纳米给药系统,探索肿瘤细胞药物摄取增加与细胞膜的关系及相关机制。参与国家自然科学基金面上项目1项。近五年以第一作者身份发表一区 SCI 论文2篇, 以共同作者身份发表 SCI 论文 7 篇。承担《药剂学》、《药剂学实验》、《生物药剂学与药物动力学》等课程教学。
发表论文
近五年代表文章
1. Mei-Qi Xu; Ting Zhong; Xin Yao; Zhuo-Yue Li; Hui Li; Jing-Ru Wang; Zhen-Han Feng; Xuan Zh ang ; Effect of XlogP and hansen solubility parameters on the prediction of small molecule modifi ed docetaxel, doxorubicin and irinotecan conjugates forming stable nanoparticles, Drug Delivery, 2021, 28(1): 1603-1615
2. Mei-Qi Xu; Yan-Li Hao; Jing-Ru Wang; Zhuo-Yue Li; Hui Li; Zhen-Han Feng; Hui Wang; Jing-W en Wang; Xuan Zhang ; Antitumor Activity of α-Linolenic Acid-Paclitaxel Conjugate Nanoparticles: In vitro and in vivo, International Journal of Nanomedicine, 2021, 16: 7269-7281
3. Xiao-Chuan Duan; Li-Yuan Peng; Xin Yao; Mei-Qi Xu; Hui Li; Shuai-Qiang Zhang; Zhuo-Yue Li ; Jing-Ru Wang; Zhen-Han Feng; Guang-Xue Wang; Ai Liao; Ying Chen; Xuan Zhang ; The synergistic a ntitumor activity of 3- (2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) an d anti-PD-L1 antibody inducing immunogenic cell death, Drug Delivery, 2021, 28(1): 800-813
4. Shuang Zhang; Zhan-Tao Li; Man Liu; Jing-Ru Wang; Mei-Qi Xu; Zhuo-Yue Li; Xiao-Chuan Duan ; Yan-Li Hao; Xiu-Chai Zheng; Hui Li; Zhen-Han Feng; Xuan Zhang ; Anti-tumour activity of low mol ecular weight heparin doxorubicin T nanoparticles for histone H1 high-expressive prostate cancer PC-3M cells, Journal of Controlled Release, 2019, 295: 102-117
5. Xiao-Chuan Duan; Xin Yao; Shuang Zhang; Mei-Qi Xu; Yan-Li Hao; Zhan-Tao Li; Xiu-Chai Zhen g; Man Liu; Zhuo-Yue Li; Hui Li; Jing-Ru Wang; Zhen-Han Feng; Xuan Zhang ; antitumor activity of the bioreductive prodrug 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPa-PTX NPs)
教学与课程
目前担任本科生课程:《药剂学》、《药剂学实验》、《生物药剂学与药物动力学》、《生物药剂学与药物动力学实验》的本科教学。