高延盼 博士
讲师
临床医学系教师
电话:13693349663 邮箱:gaoyp@zucc.edu.cn 办公地址:新葡萄8883官网AMG北校区理2-519
研究方向:神经退行性疾病研究
个人简介
高延盼,讲师,硕士生联合导师。研究神经退行性疾病及骨代谢失调等衰老相关疾病的机制研究。主持国自然基金和北自然基金各一项,发表科技论文15篇,其中以第一作者或通讯作者发表6篇。
科研项目
1. 国家自然科学基金青年项目,项目名称:“DOT1L介导肌肉细胞线粒体通透性在骨质疏松的分子机制研究”,项目编号:81902258,在研,主持。
2. 北京市自然科学基金青年项目,项目名称:“DOT1L介导的吞噬活性失调在破骨细胞分化中的表观调控研究”,项目编号:7192127,结题,主持。
发表论文
近五年代表文章
1. Gao, Y.*, Liu, J.*, Wang, J.*, Liu, Y., Zeng, L.#, Ge, W.# and Ma, C. #(2022) Proteomic analysis of human hippocampal subfields provides new insights into the pathogenesis of Alzheimer's disease and the role of glial cells. Brain Pathol. Jul;32(4):e13047. (第一作者,JCR一区)
2. Xie, Y.*, Gao, Y.*, Zhang, L.*, Ge, W.#, and Tang, P.# (2018). Involvement of serum-derived exosomes of elderly patients with bone loss in failure of bone remodeling via alteration of exosomal bone-related proteins. Aging cell. Mar 30:e12758. (共同第一作者,JCR一区)
3. Gao, Y.* and Ge, W.# (2018). Histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis. Cell death & disease 9, DOI 10.1038/s41419-017-0040-5. (第一作者,JCR一区)
4. Gao, Y.*, Chen Y.*, Wang, L., Li, C.#, Ge, W.# (2021). Serum-derived extracellular vesicles inhibit osteoclastogenesis in active phase-patients with SAPHO syndrome. Therapeutic Advances in Musculoskeletal Disease
5. Chen, Y.*, Xie, Y.*, Xu, L.*, Zhan, S., Xiao, Y., Gao, Y.#, Wu, B.#, and Ge, W.# (2017). Protein content and functional characteristics of serum-purified exosomes from patients with colorectal cancer revealed by quantitative proteomics. International journal of cancer 140, 900-913. (共同通讯作者,JCR一区)
6. Xu, B.*, Gao, Y.*, Zhan, S., and Ge, W.# (2017). Quantitative proteomic profiling for clarification of the crucial roles of lysosomes in microbial infections. Molecular immunology 87, 122-131. (共同第一作者)
教学与课程
目前担任本科生课程:《医学免疫学(甲)》、《微生物学与免疫学》和《医学微生物学及免疫学实验》的本科教学。